Introduction
In treatment and management of Irritable Bowel Syndrome (IBS) does supplementation of Vitamin D in children with other chronic diseases help as opposed to not administering the supplement? Health care providers and researchers should evaluate the effect of prescribing Vitamin D supplement to children with other chronic diseases. IBS is prevalent in those who pathogenesis has been poorly explained. The relationship between IBS and Vitamin D supplement has only been studied in patients identified to have IBS and not those with IBS and other chronic diseases.
The nursing profession is a vital arm of medicine as nursing professionals interact with the patients almost in a day to day basis. Once a physician has treated a patient and prescribed the proper treatment plan, nursing professionals oversee the rest of the process. As such, any changes whether nurses, this kind of observation first notice side effect, deterioration, improvement can be helpful to healthcare researchers and physicians in changing the course of treatment, identifying potential research areas, the nursing professionals may even take part in the research. It is essential to the nursing profession to establish the effect of Vitamin D supplementation on IBS patients who have been recorded to have other illnesses.
Literature Review
Teitelbaum, Sinha, Micale, Yeung & Jaeger, (2009) compile an article reviewing the effect of obesity in abdominal diseases; they confirm that obesity affects the gastrointestinal (GI) function thereby contributing to gastrointestinal infections and especially in children. Three groups, Gastrointestinal group (GI), Local control group and another group NJ of children identified as obese were used. The GI group sample that complained of significant intestinal problems like constipation, abdominal pain, IBS were significantly high.
Similarly, pain associated with gastrointestinal disorders like IBS affect an unprecedented massive number of children than expected as explained by El-Chammas, Majeskie, Simpson, Sood & Miranda, (2013) in their journal, "Red Flags in Children with Chronic Abdominal Pain and Crohn's Disease-A Single Center Experience" Patients seen at pediatric gastroenterology clinic at Children's Hospital of Wisconsin completed the demographics of patients with abdominal pain for over a month. Six hundred six patients reported to have Crohn's disease, and chronic abdominal pain had their data collected; they had functional gastrointestinal disorders and higher chances of having come from families that had a history of IBS. Anemia, weight loss helped identify patients with chronic abdominal pain making it necessary to refer for further check by a gastroenterologist.
Hosseinzadeh, Poorsaadati, Radkani, & Forootan (2011) have enumerated the correlation between psychological disorder in patients with chronic constipation which is most times a characteristic of irritable bowel syndrome. Fifty-four constipated patients were screened for psychiatric disorders and showed high levels of anxiety and stress disorders. The conclusion was to reduce healthcare costs for sick patients; a psychological dysfunction program needs to be set up and address mental disorders before they cause other health issues.
Williams, Williams & Corfe, (2018) have shared results from their study; the role of Vitamin D in IBS and its association with Colorectal cancer. They posit that there is limited information on Vitamin D and management of colorectal conditions like colorectal cancer. Cause and effect may be difficult to arbitrate behavioral changes are recorded in people with IBS; like spending time indoors which will subsequently affect their Vitamin D levels. (Williams, Williams & Corfe, 2018) conclude that more studies should be conducted to find out the relationship between Vitamin D and gastrointestinal disorders thereby advising research into possible ways of managing other illnesses like Colorectal cancer.
Kari, (2012) investigated the effect of oral administration of vitamin D3 to children with chronic kidney disease (CKD) and the conclusion was that it resulted in significant improvement of Vitamin D levels in the children but did not lead to normalization. The researcher's conclusion was low doses will not be sufficient for normalization and therefore recommended high doses to be served for the desired outcome.
Discussion
The five examples of studies conducted on different patients present different variables that every research has focused on. This type of study matters and it is essential to identify whether it was a controlled study or not. The patients used as the subject is another variable. IBS and Vitamin D supplementation has been recorded to have different outcomes in children, adolescents, and adults. The studies have also tried to discuss the relationship between IBS and Vitamin D. Although there is a clear correlation between the two that has been reported, the reviews try to explain and give a recommendation for more research to be conducted in that area.
Studies have similarities of findings which are that Vitamin D administration presented more positive results as opposed to injection of placebo treatment. The findings were consistent with geolocation and exposure to sunlight of the patients. Areas, where patients had access to sunlight throughout the trial period, presented improvements which researchers attribute to influences of sunlight. Further, the researchers have been keen to point out that more research should be done in different locations with different weather patterns.
The discussion about the effectiveness of Vitamin D supplementation on children who present IBS symptoms and have other diseases is critical. Psychological disorders are a vital example of how they can contribute to IBS and other gastrointestinal illnesses. Anxiety, stress, and depression were recorded in patients with constipation and other forms of abdominal diseases indicating a correlation albeit not scientifically proven that reduced Vitamin D responsible for preventing IBS lead to psychological disorders. Conclusion
Healthcare givers and researchers should conduct further research on the correlation between IBS and Vitamin D and further identify the effects of its administration and supplementation on children with other chronic diseases. The analysis will identify and collect essential data that will help develop better healthcare mechanisms for affected children.
Researchers should have included studies/trials done in different areas, on patients with various conditions present IBS symptoms and compare the findings. While this may be difficult for one researcher to coordinate, it is a call to scientists all over the world to conduct research and share results on IBS, Vitamin D, and patients with chronic diseases.
1. Amrousy EL Doaa, Hassan Samil, Ashry El Heba, Yousef Mohamed, Hodeib Hossan To evaluate the effects of Vitamin D supplementation in adolescents with IBS and Vitamin D deficiency Randomized Controlled Trial One hundred and twelve adolescents with IBS and Vitamin D deficiency divided into two groups of age and sex Quantitative Adolescents who received Vitamin D treatment showed an increased serum of Vitamin D compared to the placebo group. Anxiety and depression were recorded as major psychological elements from the beginning of IBS symptoms, and Vitamin D helps reduce anxiety levels and depression and is recorded as the explanation in the group served with vitamin D. Vitamin D in IBS patients can act through ameliorating their anxiety, stress, depression and eventually improving quality of life
2. A. Abbasnezhad, R. Amami, E. Hassani, P. Alavinejan, B. Cherachian, A.Ghadiri Effects of Vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients Randomized double-blind clinical trial 90 randomly selected IBS patients Quantitative The mean change is Serum D was higher in the Vitamin D treatment group as opposed to the placebo group. IBS symptoms such as pain, flatulence, discomfort, abdominal distention improved in both groups except for dissatisfaction with the bowel but were more significant in the Vitamin D group. Both placebo and Vitamin D groups showed improvement; however, Vitamin D showed the most considerable improvement and a direct effect on the quality of life as it improves stress and anxiety levels which are primary contributors to IBS
3. Simon Tazzyman, Nicholas Richards, Andrew R Trueman, Amy L Evans, Vicky A Grant, Iveta Garaiova, Sue F Plummer, Elizabeth A Williams, Bernard M Corfe Association of Vitamin D in improved quality of life in participants with irritable bowel syndrome in a pilot trial Randomized, double-blinded, three arm parallel design trial 51participants were given Vitamin D dose, placebo or both over six months. A significant proportion of the IBS patients were Vitamin D depleted. Supplementation significantly increased Vitamin D level versus placebo. Vitamin D deficient diet may directly impact bowel function and hence IBS symptomology.
4. Helen M. Pappa, Paul D. Mitchell, Hongyu Jiang, Sivan Kassiff, Rajna Filip-Dhima, Diane DiFabio, Nicolle Quinn, Rachel C. Lawton, M. E. S. Bronzwaer, Mirjam Koenen, and Catherine M. Gordon Effects of maintenance of an Optimal Vitamin D Status in Children and Adolescents With Inflammatory Bowel Disease Randomized, controlled Clinical trial. Children and adolescents with IBD Intention to treat principle Oral Vitamin D supplementation was not successful in maintaining Serum 250HD concentration of 32ng/ml. While supplementing Vitamin D, healthcare practitioners should put the body weight of the patients into consideration.
5. Mahsa Jalili, Homayoon Vahedi, Hossein Poustchi, Azita Hekmatdoos Effects of Vitamin D Supplementation in Patients with Irritable Bowel Syndrome in Women The practitioners performed random clinical trials controlled by placebo. 116 patient were given Vitamin D supplements. They all had IBS. Quantitative analysis and intention to treat analysis with Vitamin D therapy has beneficial effects in the management of IBS in women. Vitamin D can improve IBS symptoms as it reduces all known risk factors.
References
El-Chammas, K., Majeskie, A., Simpson, P., Sood, M., & Miranda, A. (2013). Red Flags in Children with Chronic Abdominal Pain and Crohn's Disease-A Single Center Experience. The Journal Of Pediatrics, 162(4), 783-787. doi:10.1016/j.jpeds.2012.09.014
Hosseinzadeh, S. T., Poorsaadati, S., Radkani, B., & Forootan, M. (2011). Psychological disorders in patients with chronic constipation. Gastroenterology and Hepatology from bed to the bench, 4(3), 159-163.
Kari, J. A., Eldesoky, S. M., & Bagdadi, O. T. (2012). Vitamin D insufficiency and treatment with oral vitamin D3 in children with chronic kidney disease. Saudi medical journal, 33(7), 740-744.
Teitelbaum, J., Sinha, P., Micale, M., Yeung, S., & Jaeger, J. (2009). Obesity is Related to Multiple Functional Abdominal Diseases. The Journal Of Pediatrics, 154(3), 444-446. doi: 10.1016/j.jpeds.2008.09.053
Williams, C., Williams, E., & Corfe, B. (2018). Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what do we need to know?. European Journal Of Clinical Nutrition, 72(10), 1358-1363. doi: 10.1038/s41430-017-0064-z
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