Preparing African Women for PrEP: Rethinking HIV Prevention - Annotated Bibliography

Kurth, A., Bukusi, E., Desmond, C., Morton, J., & Baeten, J. M. (2015). Rethinking HIV prevention to prepare for oral PrEP implementation for young African women. Journal of the International AIDS Society, 18(4 (Suppl 3)), 126-261. https://doi.org/10.7448/IAS.18.4.20227

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Celum et al. (2015) showed a high HIV incidence among the Sub-Saharan Africa population with scale-up HIV testing. The study showed the critical need for criticizing past approaches while implementing the compelling evidence-based HIV prevention strategies for the merging pre-exposure prophylaxis. The review on the behavioral and biomedical approaches to HIV prevention entailed addressing particular criteria with the implementation of PreP to address the broader sexual norms and expectations based on the increased risk and vulnerability. The HIV prevention strategy with the oral PreP has evidence for protection with the high efficacy and effectiveness of the population.

Wheelock, A., Eisingerich, A. B., Gomez, G. B., Gray, E., Dybul, M. R., & Piot, P. (2017). Views of policymakers, healthcare workers, and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study. BMJ Open, 2(4), e001234. https://doi.org/10.1136/bmjopen-2012-001234

Wheelock et al. (2017) aimed at examining the policies and views on the pre-exposure prophylaxis practice in HIV prevention. The study employed a qualitative interview study on the policymakers, healthcare workers, and the organizational representation for HIV prevention. The results revealed the perceived HIV prevention landscape and the need for active prevention initiatives need to improve the conditions with the PrEP awareness. The benefits of the PrEP range from the components of combination prevention to the prioritization of HIV prevention. The PrEP initiative entails empowering the population for economic gain due to its efficacy and effectiveness.

Curran, K., Baeten, J. M., Coates, T. J., Kurth, A., Mugo, N. R., & Celum, C. (2017). HIV-1 Prevention for HIV-1 Serodiscordant Couples. Current HIV/AIDS Reports, 9(2), 160-170. https://doi.org/10.1007/s11904-012-0114-z

The HIV prevention strategies entail a stable relationship with the HIV uninfected partners. Curran et al. (2017) targeted the discordant couples as the population for prevention based on the testing and counseling facilities and identification of the risk reduction and treatment and reproductive health services. Therefore, maximizing the prevention for the HIV discordant couples, which requires a combination of strategies, including the oral PrEp services to prevent the transmission.

Maier, J. P., & Muller, J. F. (2016). The assignment of the photoelectron spectra of pyridine-N-oxides. Tetrahedron Letters, 15(35), 2987-2990. https://doi.org/10.1016/S0040-4039(01)91800-3

Maier and Muller (2016) evaluated the pre-exposure prophylaxis for HIV prevention basing on the clinical practice guidelines. The study provided a piece of comprehensive information for the use of oral PrEP for reducing the risks of acquiring HIV infection. The instructions entailed daily oral PrEP, which is recommended as effective in decreasing the risk of sexual acquisition adults. The study suggests PrEP as one prevention option of the risk of HIV, especially for HIV discordant couples. The risks and benefits of PrEP are weighed in the context of the regulations on the health care decisions making by minors. The medication approved is recommended for the PrEP with the specification of guidelines for substantial efficacy and safety.

Tetteh, R. A., Yankey, B. A., Nartey, E. T., Lartey, M., Leufkens, H. G. M., & Dodoo, A. N. O. (2017). Pre-Exposure Prophylaxis for HIV Prevention: Safety Concerns. Drug Safety, 40(4), 273-283. https://doi.org/10.1007/s40264-017-0505-6

The evidence supporting the efficacy of pre-exposure prophylaxis (PrEP) shows that it decreases the incidences of HIV infection among high-risk individuals (Tetteh et al., 2017). Although the safety concerns have been an issue in the implementation of the PrEP, it has received global advocacy for HIV prevention. The purpose of the pre-exposure prophylaxis, therefore, ensures an effective routine for real-life practice while moderating the various effects, including nausea, vomiting, and diarrhea. Therefore, PrEP is an essential intervention for reducing HIV transmission and has a safety benefit-risk profile in the clinical trials with adherence to monitoring real-world safety surveillance.

Matthews, L. T., Baeten, J. M., Celum, C., & Bangsberg, D. R. (2015). Preconception pre-exposure prophylaxis to prevent HIV transmission: benefits, risks, and challenges to implementation. AIDS, 24(13), 1975-1982. https://doi.org/10.1097/QAD.0b013e32833bedeb

Matthews et al. (2015) studied the benefits of pre-exposure prophylaxis in preventing HIV transmission, revealed the intervention's benefits in helping couples fulfill their reproductive desire while preventing the risks of HIV transmission. The study proposed the preconception pre-exposure prophylaxis (PrEP), which offers complementary therapy to reducing the counseling program while decreasing the HIV transmission. The study considered the transmission risk and PrEP efficacy as well as the cost and impact of PrEP on the entry into health services.

Koester, K., Amico, R. K., Gilmore, H., Liu, A., McMahan, V., Mayer, K., Hosek, S., & Grant, R. (2017). Risk, safety, and sex among male PrEP users: time for a new understanding. Culture, Health & Sexuality, 19(12), 1301-1313. https://doi.org/10.1080/13691058.2017.1310927

Koester et al. (2017) revealed HIV prevention with the biomedical, leading to an optimistic projection. The study showed optimism concerns for the protective benefits such as technology and the HIV pre-exposure prophylaxis, which contributes to the understanding of safety concepts and risk on HIV PrEp. Through the PrEP intervention, the patients experience relief and a sense of reprieve from HIV related stress.

References

Celum, C. L., Delany-Moretlwe, S., McConnell, M., van Rooyen, H., Bekker, L.-G., Kurth,.,Bukusi, E., Desmond, C., Morton, J., & Baeten, J. M. (2015). Rethinking HIV prevention to prepare for oral PrEP implementation for young African women. Journal of the International AIDS Society, 18(4 (Suppl 3)), 126-261. https://doi.org/10.7448/IAS.18.4.20227

Curran, K., Baeten, J. M., Coates, T. J., Kurth, A., Mugo, N. R., & Celum, C. (2017). HIV-1 Prevention for HIV-1 Serodiscordant Couples. Current HIV/AIDS Reports, 9(2), 160-170. https://doi.org/10.1007/s11904-012-0114-z

Koester, K., Amico, R. K., Gilmore, H., Liu, A., McMahan, V., Mayer, K., Hosek, S., & Grant, R. (2017). Risk, safety, and sex among male PrEP users: time for a new understanding. Culture, Health & Sexuality, 19(12), 1301-1313. https://doi.org/10.1080/13691058.2017.1310927

Maier, J. P., & Muller, J. F. (2016). The assignment of the photoelectron spectra of pyridine N-oxides. Tetrahedron Letters, 15(35), 2987-2990. https://doi.org/10.1016/S0040-4039(01)91800-3

Matthews, L. T., Baeten, J. M., Celum, C., & Bangsberg, D. R. (2015). Preconception pre exposure prophylaxis to prevent HIV transmission: benefits, risks, and challenges to implementation. AIDS, 24(13), 1975-1982. https://doi.org/10.1097/QAD.0b013e32833bedeb

Tetteh, R. A., Yankey, B. A., Nartey, E. T., Lartey, M., Leufkens, H. G. M., & Dodoo, A. N. O. (2017). Pre-Exposure Prophylaxis for HIV Prevention: Safety Concerns. Drug Safety, 40(4), 273-283. https://doi.org/10.1007/s40264-017-0505-6

Wheelock, A., Eisingerich, A. B., Gomez, G. B., Gray, E., Dybul, M. R., & Piot, P. (2017). Views of policymakers, healthcare workers, and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study. BMJ Open, 2(4), e001234. https://doi.org/10.1136/bmjopen-2012-001234