Paper Example on Unravelling the Pathophysiologya of Onychomycosis

The main problem is to study changes of the typical mechanical, physical and biochemical function caused by the onychomycosis from an abnormal syndrome.The main graze of onychomycosis, in this case, exists as acanthosis, spongiosis, papillomatosis with oedema, and hyperkeratosis (Morris-Jones, 2019). The grazes justify the sense of pathophysiology of the disease primarily occurs in the nails of an individual. As the infection grows, the pathogens cause a dense inflammatory infiltrate, which appears on the nails of a person. The nail beds become hyperkeratotic and thick, which can shelter fungal infection (Morris-Jones, 2019). The nails get distorted and detachedby the dermatophytes of the disease over time and further elevate and misalign as the disease enters the critical stage of Total Dystrophic Onychomycosis (Morris-Jones, 2019). The other justification gets displayed where the chronic stage encompassesa large amount of compact hypergranulosis, acanthosis, hyperkeratosis, and papillomatosis with sparse perivascular infiltrate (Morris-Jones, 2019). The analysis has shown the critical pathophysiology study, which is relevant for this case.

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The primary physical examination and diagnostic findings of onychomycosis are such as white-yellow or orange-brown streaks in a longitude manner located at the nails of an individual (Lipner&Scher, 2019). It shows the presence of dermatophyte, which justifies the existence of onychomycosis in the nail. The other examination of the disease is the subungual, onycholysis, nail thickening and crumbling, and hyperkeratosis (Lipner&Scher, 2019). There may be an existing scale in the web spaces and plantar feet. The diagnostic findings on the disease mainly state that it is a fungal infection of the nail. It gets caused by organisms but primarily by dermatophytes. The system diagnosis is effective as it encompasses 63% for itraconazole with pulse dosing, 76% for terbinafine and 49% for fluconazole can help cure the disease (Lipner&Scher, 2019).

The evidence-based treatment plans are; oral therapy which involves the use of drugs, and the topical therapy that will help in the treatment of nail fungus (Lipner, 2019). The patient may undergo counselling due to the appearance of the feet to identify any mental disturbance before treatment. The patient can get advice and knowledge forms the healthcare giver to avoid contact with impure water during swimming and bathing occasions (Lipner, 2019). It is significant as it prevents undesirable outcomes of the onychomycosis disease to an individual.

References

Lipner, S. R. (2019). Pharmacotherapy for onychomycosis: new and emerging treatments. Expert opinion on pharmacotherapy, 20(6), 725-735.

Lipner, S. R., &Scher, R. K. (2019). Onychomycosis: Clinical overview and diagnosis. Journal of the American Academy of Dermatology, 80(4), 835-851.

Morris-Jones, R. (2019). ABC of Dermatology. John Wiley & Sons.